Entire Care Systems, Inc.  ·  Est. 2026

Care that sees
the whole
person.

Infrastructure for people managing multiple chronic conditions.

Entire Care Systems is building CECE — patient-directed chronic care governance infrastructure that coordinates multi-morbidity care across fragmented health systems. We start where the burden is greatest, prove what works, and scale.

The Problem We're Solving

Patients managing multiple chronic conditions must navigate fragmented specialists, contradictory medications, and siloed records — with no coordination infrastructure and no support.

WITHOUT CECE Patient Spec 1 Spec 2 Pharm PCP WITH CECE Patient Spec 1 Spec 2 Pharm PCP
1 in 4
Adults in the U.S. live with multiple chronic conditions
$4.1T
Annual U.S. healthcare spend — majority on chronic care
71%
Of preventable hospitalizations linked to care fragmentation
Phase 0
Western Kenya target site · Nigeria Phase II planned · 2026

A healthcare
infrastructure
company.

Entire Care Systems, Inc. (ECS) is the company. CECE is our product — a patient-directed care coordination framework built to solve one of healthcare's most persistent failures: the burden placed on patients to coordinate their own multi-condition care across fragmented systems.

We are a pre-revenue, pre-seed stage company founded in 2026 and headquartered in the United States, operating under the leadership of our Founder and CEO, Marshall G. Jackson, DM, MBA.

2026
Year founded by Marshall G. Jackson, DM, MBA
Pre-Seed
Funding stage · Q2 2026 target close
2 Markets
Kenya (pilot) → United States (scale)

No one should be their own systems integrator just to manage a chronic condition.

Entire Care Systems exists to build the coordination infrastructure that patients with multiple chronic conditions deserve but have never had. Our mission is to reduce the burden of care fragmentation — not by adding another app, but by creating a governance framework that puts patients at the center of their care ecosystem.

We do this through CECE: a structured, evidence-based coordination model that aligns specialists, pharmacies, caregivers, and community supports into a coherent whole — directed by the patient, not dictated to them.

A world where multi-morbidity is manageable.

We envision health systems where the coordination of complex, chronic care is embedded as infrastructure — the same way roads, utilities, and communication networks are embedded in how societies function.

CECE's Phase 0 pilot targets Western Kenya — where multi-morbidity coordination failure is most acute and most documented. ECS is seeking formal collaboration in this environment as its first validation site. Phase II outreach is planned in Nigeria through the Nigerian Institute of Medical Research (NIMR) and University College Hospital, Ibadan. That two-country evidence base then travels to the United States, and beyond.

What we stand for.

Patient Direction
Care coordination must be governed by the person receiving care — not prescribed to them. CECE places decision authority with patients.
Evidence First
Every design decision in CECE is grounded in implementation science, doctoral-level research, and real-world validation — not assumption.
Systems Thinking
We treat care as an ecosystem. Fragmentation isn't a provider failure — it's an infrastructure failure. We build the infrastructure.
Global → Local
Proving the model where the burden is highest creates durable evidence. Kenya first — not as charity, but as rigorous validation.
Equity by Design
Low-income and underserved populations bear the greatest burden of fragmented care. CECE is built for them first — not added as an afterthought.
Accountability
We are pre-revenue and transparent about it. We commit to measurable outcomes, honest milestones, and responsible stewardship of every dollar invested.

The essentials for funders & partners.

Legal Name
Entire Care Systems, Inc.
U.S. Corporation
Stage
Pre-Revenue
Phase 0 · Pre-Seed Fundraising
Founded
2026
By Marshall G. Jackson, DM, MBA
Product
CECE
Chronic care coordination framework
First Market
Western Kenya
Western Kenya · Target collaboration site
Target Market
United States
Medicaid MCOs, ACOs, FQHCs
Raise Target
Pre-Seed Round
Q2 2026 target close
Grant Eligible
Yes
Global health, USAID, Gates, NIH SBIR
Explore the Full Picture
CECE Framework
The six universal pillars of patient-directed chronic care coordination.
Explore →
Traction & Market
Milestones achieved, market size, and our business model.
View →
Connect with ECS
Investment inquiries, grant partnerships, health system pilots.
Connect →

CECE — a new
coordination
infrastructure.

CECE (Chronic Entire Care Ecosystem) is a patient-owned, interoperable, context-adaptive coordination architecture — not an app or dashboard, but a governance framework built on six universal pillars. The patient retains ownership and control of their longitudinal health data, ensuring portability across care settings, institutions, and national borders. Context-specific adaptations enhance functionality without altering the core architecture. Built on doctoral research and validated through implementation science.

6
Universal architecture pillars structuring every care plan
AI + Human
Hybrid model — AI-assisted coordination, patient-governed, clinician-accountable
2 Models
Advanced Health System & LMIC Adaptation — same pillars, context-specific features

Six pillars. One whole person.

The six pillars form a Universal Architecture Layer — applicable across both advanced health systems and resource-constrained LMIC environments. The patient sits at the center, holding a Personal Longitudinal Health Vault that travels with them across every care setting, institution, and national border.

01
Upstream & Coexisting Conditions
Maps the full constellation of a patient's co-occurring chronic conditions — including social determinants, upstream risk factors, and condition interactions — so care plans reflect the whole clinical picture, not isolated diagnoses treated in silos.
02
Medication Ecosystem
Coordinates the full medication landscape across prescribers, pharmacies, and care settings. Identifies polypharmacy risks, drug-condition conflicts, adherence barriers, and opportunities for Essential Medicines List alignment in resource-limited environments.
03
Partnership & Communication
Structures the communication ecosystem between the patient and all care partners — specialists, primary providers, community health workers, and caregivers — using defined protocols, audit trails, and consent-based information sharing.
04
Education & Translation
Delivers condition-specific health education adapted to patient literacy, language, and context. In LMIC settings, this includes low-literacy formats, SMS-based alerts, and community health worker-mediated instruction — ensuring knowledge reaches the patient, not just the chart.
05
Lifestyle Infrastructure
Addresses the behavioral, social, and environmental factors that shape chronic disease outcomes — nutrition, physical activity, mental health, housing stability, and community support — integrating them into the care coordination framework as first-class clinical inputs.
06
The Patient — Personal Longitudinal Health Vault
The patient is not just the recipient of care — they are the governance center. The Personal Longitudinal Health Vault gives patients portable, institution-independent ownership of their health record, with audit logs, attribution tracking, emergency override governance, and no single institutional point of control.

Two Deployment Models. One Universal Architecture. CECE adapts to context without changing its core.

CECE — Advanced Health System Model: Specialty-driven EHR integration, risk stratification analytics, insurance optimization, remote monitoring, and appointment intelligence — for high-resource U.S. and global health systems.

CECE — LMIC Adaptation Model: Community health worker integration, Essential Medicines List coordination, SMS-based alerts, low-literacy education formats, and medication stock monitoring — purpose-built for resource-constrained environments like Western Kenya.

Both models share the same six-pillar Universal Architecture Layer and interoperability foundation — Standards-Based APIs, Audit Trails, and Security Controls — ensuring evidence and outcomes transfer across contexts.

Prove globally.
Scale nationally.

ECS deliberately begins its validation in a resource-constrained, high-burden environment — Western Kenya, where ECS is seeking formal collaboration with established health system partners. This is not altruism; it is rigorous strategy. Proving that CECE reduces fragmentation and improves outcomes in the world's most demanding context creates the highest-quality evidence base for U.S. market entry. Phase II outreach is planned in Nigeria — building a two-country evidence pathway that significantly strengthens the Gates Foundation funding case.

Phase 1
Kenya Validation
(2025–2026)
Pilot CECE with multi-morbidity patients at target facilities in Western Kenya. Measure coordination outcomes, patient burden reduction, and system integration.
  • Established health system research infrastructure
  • IRB-ready protocol development
  • Multi-morbidity focus: HIV + diabetes + hypertension
  • Publication and outcomes documentation
Phase 2
U.S. Market Entry
(2026–2027)
Enter the U.S. market through Medicaid managed care organizations, Federally Qualified Health Centers, and Accountable Care Organizations where chronic care coordination ROI is most measurable.
  • Medicaid MCO licensing model
  • FQHC implementation partnerships
  • ACO value-based care alignment
  • CMMI innovation grant pathway
2
Target countries.
Kenya Phase 0 · Nigeria Phase II planned.
$147B
U.S. chronic care
coordination market (TAM)
Q2 2026
Target pre-seed
close date

From research to scale.

2022–2024 2025 2026 ←NOW 2026–2027 2027+ Research Company & IP Kenya Pilot Fundraising U.S. Entry DM · MBA · CECE Framework ✓ ECS Inc. Founded ✓ Kenya Outreach ▶ Pilot Launch & Data Pre-Seed → Seed Round ▶ MCO / FQHC Partnerships Completed In Progress Planned
⬡   Phase 0 · Active Development · 2 Countries

Western Kenya.
Nigeria next.
Evidence at scale.

CECE's Phase 0 pilot targets Western Kenya — one of the world's most rigorously documented multi-morbidity care environments — where ECS is seeking formal collaboration with established health system partners. Phase II outreach is planned in Nigeria through NIMR and the University College Hospital, Ibadan.

AMPATH
Target collaboration partner · Academic Model for Prevention & Treatment · 20+ year track record
2
Target countries · Kenya Phase 0 planned · Nigeria Phase II outreach planned
2026
IRB protocol development · Kenya + Nigeria outreach year
Global → U.S.
Two-country evidence pathway to American health system entry
Evidence Pathway
Phase 0 · Active 2026 Western Kenya Phase II · Outreach Planned Nigeria Phase 2 · 2027+ United States evidence pathway → Prove globally. Scale nationally.

Why Kenya first?

  • Documented burden: Western Kenya has one of the highest documented multi-morbidity burdens in sub-Saharan Africa — a proven proving ground for coordination interventions.
  • Target partner infrastructure: AMPATH (Academic Model for Prevention and Treatment) represents the ideal collaboration environment — with established research infrastructure, IRB capacity, patient access, and outcome measurement frameworks. ECS is seeking formal engagement with AMPATH leadership to explore this collaboration.
  • Transferable evidence: Resource-constrained environments strip coordination to its essentials — making insights directly applicable to underserved U.S. populations where care fragmentation is equally severe.
  • Grant alignment: Gates Foundation, USAID, and Wellcome Trust all prioritize multi-morbidity coordination research in LMICs — creating a natural funding runway for pilot phases.
  • Publication pathway: AMPATH's academic partnerships with Indiana University and Moi University create clear pathways to peer-reviewed publication — a key reason ECS is pursuing collaboration in this environment. Published outcomes are the gold standard for credibility with U.S. payers and health systems.
Why AMPATH Is ECS's Target Partner

AMPATH (Academic Model Providing Access to Healthcare) is one of Africa's largest and most studied health delivery programs, operating in Western Kenya since 2001 in partnership with Moi University, Moi Teaching and Referral Hospital, and a consortium of North American universities led by Indiana University.

AMPATH has served over 160,000 patients and built one of the continent's most sophisticated health information systems — making it the ideal target collaboration context for CECE's coordination infrastructure.

No formal partnership exists at this time. ECS is in early-stage outreach to explore potential collaboration. IRB and ethics review processes will be initiated prior to any patient-facing activity, subject to formal agreement being reached.

Nigeria is a planned Phase II target — through the Nigerian Institute of Medical Research (NIMR) and the University College Hospital, Ibadan. A two-country evidence base strengthens the Gates Foundation funding pathway.

The Evidence Pathway
Validation in Kenya creates the evidence base for U.S. market entry
FOUNDATION Doctoral Research DM + MBA · 2022–2026 Evidence-based CECE framework architecture Phase 0 KENYA PILOT · 2026 Western Kenya Western Kenya · IRB Protocol 50–200 multi-morbidity patients · HIV + DM + HTN IN PROGRESS Phase 1 PUBLICATION · 2026–2027 Peer-Reviewed Outcomes Indiana Univ · Moi Univ Gold-standard payer evidence PLANNED Phase 2 U.S. ENTRY · 2027+ Medicaid MCOs & FQHCs $147B TAM Value-based care entry SCALE

Where we are.
Where we're going.

Entire Care Systems is pre-revenue and proud of its transparency. Below is an honest account of what has been built, what is underway, and what investment or grant funding will unlock. We believe the strongest case for early-stage support is intellectual honesty about the journey.

Milestones & roadmap.

Completed · 2022–2024
Doctoral Research Foundation
Marshall G. Jackson completed doctoral research (DM, MBA) examining why well-intentioned healthcare interventions fail — identifying care coordination failure as the root cause, not patient motivation. This research forms CECE's evidence backbone.
Completed · 2026
CECE Framework Architecture
Full conceptual architecture of the five-pillar CECE framework completed. Governance model, patient-direction principles, and coordination protocols defined. Framework documentation prepared for clinical and investor review.
Completed · 2026
Company Formation
Entire Care Systems, Inc. formally established. Legal structure in place. Founder and CEO credentialed and operational. Initial branding, positioning, and investor-facing materials developed.
In Progress · 2026
Western Kenya Collaboration Outreach
Early-stage outreach to health system partners in Western Kenya to explore formal collaboration for CECE's Phase 0 pilot. IRB preparation and site-readiness planning underway pending partnership agreement.
In Progress · 2026
Nigeria Phase II — NIMR & UCH Ibadan Outreach Planned
Letter of Intent outreach initiated to the Nigerian Institute of Medical Research (NIMR) and University College Hospital, Ibadan — establishing a two-country evidence pathway for the Gates Foundation funding application. Nigeria Health Watch engaged as a connector. NIMR has an established relationship with the Bill & Melinda Gates Foundation.
In Progress · 2026
Pre-Seed Fundraising & Grant Applications
Actively pursuing pre-seed investment (target close Q2 2026) and submitting to global health grant programs including Gates Foundation Grand Challenges, NIH SBIR, and USAID Development Innovation Ventures.
Planned · 2026
Kenya Pilot Launch & Data Collection
CECE piloted with 50–200 multi-morbidity patients at target facilities in Western Kenya, subject to formal collaboration agreement. Primary outcomes: care coordination score improvement, provider-patient alignment, medication conflict reduction.
Planned · 2026–2027
Publication & U.S. Market Entry
Peer-reviewed publication of Kenya pilot results. Nigeria Phase II pilot launch upon formal agreement. Gates Foundation Grand Challenges application submitted with two-country evidence base. First U.S. health system or FQHC partnership signed. Seed round open. CECE v1.0 product launch.

The size of the problem.

Total Addressable Market (U.S.)
$147B
Annual U.S. spending on chronic disease management and care coordination for adults with multiple conditions. Growing at ~6% annually as the multi-morbidity population expands.
Serviceable Addressable Market
$18B
Medicaid MCOs, FQHCs, and ACOs serving multi-morbidity patients where coordination infrastructure investment is reimbursable, measurable, and actively sought.
Global Health Grant Market
$2.4B
Annual global health funding targeting multi-morbidity and chronic care coordination in LMICs from Gates Foundation, USAID, Wellcome Trust, and bilateral donors.
Population Served (U.S.)
129M
Americans living with at least one chronic condition. Of these, an estimated 45M manage two or more conditions with minimal coordination support.
Market Size — Visual Comparison
TAM (U.S.) SAM Global Grants $147B $18B $2.4B $0 Growing ~6% annually Total

How Entire Care Systems generates revenue.

Health System Licensing
CECE licensed to Medicaid MCOs, ACOs, and integrated health systems on a per-patient or population-based fee model. Aligns with value-based care incentives — systems pay for reduced fragmentation and lower total cost of care.
FQHC Implementation
Federally Qualified Health Centers receive CECE as a coordination layer under a grant-subsidized implementation model, transitioning to institutional licensing upon demonstrated outcomes — reducing their PMPM costs and improving HRSA quality metrics.
Global Health Grant Revenue
In the global health market, CECE operates on a grant-funded model through agencies including Gates Foundation, USAID, and Wellcome Trust — generating revenue while building the evidence base that accelerates U.S. commercial adoption.

The people building
Entire Care Systems.

ECS is founder-led. Marshall G. Jackson brings a rare combination of healthcare technology operations, doctoral research expertise, and lived experience with care fragmentation. We are actively building our advisory board and leadership team.

MJ
Marshall G. Jackson
DM, MBA — Founder & CEO
⬡ DM ⬡ MBA ⬡ Healthcare Tech ⬡ Implementation Science
Education
Doctor of Management (DM)
Master of Business Administration (MBA)
Background
Healthcare Technology Operations
45-person team leadership
Research Focus
Chronic care coordination failure
Implementation science
Pilot Partnership
Western Kenya · Target pilot site
The Story Behind CECE

Fifteen years building
healthcare systems.
Then my mother got sick.

I spent fifteen years coordinating 45-person teams across complex healthcare technology ecosystems. I understood, at a technical and operational level, what it took to keep large systems running. Then my mother was diagnosed with multiple chronic conditions — and I watched firsthand what happens when care becomes fragmented.

Multiple specialists. Different pharmacy systems. Contradictory advice. Each provider excellent within their domain — but no one coordinating the ecosystem as a whole. The burden of integration fell entirely on her.

"I've spent fifteen years coordinating 45-person teams across complex healthcare technology ecosystems. But patients are expected to do that same coordination work — across specialists, medications, and conflicting advice — with no training and no infrastructure."

My doctoral research asked: why do well-intentioned healthcare interventions fail? The answer wasn't motivation. It was coordination. From that research — and from lived experience — CECE was born.

Now I'm building CECE beyond a framework. We're targeting Western Kenya as our first validation environment — where multi-morbidity coordination failure is most acute and most documented — and working to establish the partnerships that will make that pilot possible. Then we bring that evidence to the United States.

Because no one should have to be their own systems integrator just to manage a chronic condition.

Building an expert advisory team.

MD
Clinical Advisor · Position Open

We are seeking a physician or NP with experience in multi-morbidity chronic care management and an interest in coordination infrastructure. Contact us to discuss an advisory role.
LMIC
Global Health Advisor · Position Open

Seeking a researcher or practitioner with LMIC health systems experience — ideally with knowledge of East African health delivery context and NCD coordination in resource-constrained environments.
EQ
Health Equity Advisor · Position Open

Seeking a scholar or practitioner with expertise in health equity, social determinants, and care access for underserved U.S. populations — particularly Medicaid-enrolled adults with chronic illness.
DH
Health Tech / Digital Health Advisor · Position Open

Seeking an operator or investor with experience scaling digital health products into health systems, with familiarity with EHR integration and value-based care contracts.
IS
Implementation Science Advisor · Position Open

Seeking an academic or practitioner specializing in implementation science frameworks — supporting CECE's IRB protocols, Kenya pilot design, and publication strategy.
Interested in advising?
Advisory roles offer meaningful engagement with a mission-driven, early-stage healthcare infrastructure company at a pivotal moment.

Connect with
Entire Care Systems.

We're in active development and early conversations with funders, health system partners, and investors. Use the pathway that fits your context — we'll respond with the right information for your specific situation.

CECE does not provide medical advice, clinical support, or patient care services.

For Investors
Investment Inquiry
Pre-seed / seed round · Q2 2026 target close
For Funders
Global Health Funding
Gates Foundation, USAID, Wellcome Trust, bilateral donors
For Health Systems
Partnership Inquiry
Medicaid MCOs, ACOs, FQHCs, integrated health systems
For Researchers
Research Collaboration
Implementation science, global health, publication partnership
For Clinicians / Advisors
Advisory Role Inquiry
Clinical, global health, equity, digital health, implementation science
General
Press / Other
Media, speaking, newsletters, general questions
🎓 Doctoral-level research foundation (DM, MBA)
🌍 Western Kenya target site · Partnership outreach underway
💼 Pre-Seed · Q2 2026 target close
🔒 Professional inquiries only · No spam
✓   Thank you. We'll respond to your inquiry within 2–3 business days with the right information for your context. Investor and funder inquiries will receive materials and scheduling options within 48 hours.

For professional inquiries only. CECE is not a medical device and does not provide clinical services or advice.